Substance basis of selenium (Se) enriched green tea (Se-GT) plays a crucial role in imparting numerous health benefits to the consumer, however, the complex relationship between minerals, chemical ingredients, and Se in tea leaves remains largely unknown. Here, the contents of 14 minerals and 29 bioactive components (including 19 amino acids, 8 polyphenols, and 2 alkaloids) were determined in five green tea samples with different Se levels. Marked differences were observed in the elemental and chemical profiles of the five groups of teas. Pearson correlation analysis demonstrated that Se was l...