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Multi-omics explores the potential regulatory role of acetylation modification in flavonoid biosynthesis of Ginkgo biloba

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成果类型:
期刊论文
作者:
Liu, Xiaomeng;Ye, Jiabao;Zhang, Xiaoxi;Yang, Ke;Zheng, Jiarui;...
通讯作者:
Zhang, Weiwei;Xu, F
作者机构:
[Ye, Jiabao; Xu, Feng; Xu, F; Zhang, Xiaoxi; Yang, Ke; Zhang, Weiwei; Liu, Xiaomeng; Zheng, Jiarui] Yangtze Univ, Coll Hort & Gardening, Nanhuan Rd 1, Jingzhou 434025, Hubei Province, Peoples R China.
[Cheng, Shuiyuan; Liu, Xiaomeng] Wuhan Polytech Univ, Natl R&D Ctr Se Rich Agr Prod Proc Technol, Sch Modern Ind Selenium Sci & Engn, Wuhan 430023, Peoples R China.
通讯机构:
[Xu, F ; Zhang, WW] Y
Yangtze Univ, Coll Hort & Gardening, Nanhuan Rd 1, Jingzhou 434025, Hubei Province, Peoples R China.
语种:
英文
关键词:
CCoAOMT1 and F3′5′H;differential expression;medicinal active ingredients;molecular mechanism;post-translation level of protein
期刊:
TREE PHYSIOLOGY
ISSN:
0829-318X
年:
2024
卷:
44
期:
6
基金类别:
National Natural Science Foundation of China [32101563, 31270717]; Scientific Research Program of Hubei Provincial Department of Education [D20211301]
机构署名:
本校为其他机构
院系归属:
硒科学与工程现代产业学院
摘要:
Flavonoids are crucial medicinal active ingredients in Ginkgo biloba L. However, the effect of protein post-translational modifications on flavonoid biosynthesis remains poorly explored. Lysine acetylation, a reversible post-translational modification, plays a crucial role in metabolic regulation. This study aims to investigate the potential role of acetylation in G. biloba flavonoid biosynthesis. Through comprehensive analysis of transcriptomes, metabolomes, proteomes and acetylated proteins in different tissues, a total of 11,788 lysine acetylation sites were identified on 4324 acetylated pr...

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