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Alpinia officinarum Hance extract alleviates particulate matter-induced lung injury in mice

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成果类型:
期刊论文
作者:
Zhao, Yao-xin;Ruan, Wen-jing;Xue, Wen-lai;Zhao, Ling*
通讯作者:
Zhao, Ling
作者机构:
[Zhao, Yao-xin; Ruan, Wen-jing; Zhao, Ling; Xue, Wen-lai] Wuhan Polytech Univ, Sch Biol & Pharmaceut Engn, Wuhan, Peoples R China.
通讯机构:
[Zhao, Ling] W
Wuhan Polytech Univ, Sch Biol & Pharmaceut Engn, Wuhan, Peoples R China.
语种:
英文
关键词:
Alpinia offcinarum Hance extract;Lung injury;Particulate matter
期刊:
亚太热带医药杂志:英文版
ISSN:
1995-7645
年:
2019
卷:
12
期:
12
页码:
565-573
机构署名:
本校为第一且通讯机构
院系归属:
生命科学与技术学院
摘要:
To evaluate the effect of Alpinia officinarum Hance (A. officinarum) extract on lung injury caused by particulate matter (PM). Methods: The Kunming mice were intranasally instilled with PM and treated with A. officinarum extract for 3 weeks. Bronchoalveolar lavage fluid, blood and lung samples were collected for biochemical, serological and histopathological studies. Results: Serological analysis showed that albumin levels, lactate dehydrogenase and alkaline phosphatase activities in bronchoalveolar lavage fluid were significantly reduced after...

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