Potential hepatoprotective effects of fullerenol nanoparticles on alcohol-induced oxidative stress by ROS

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成果类型：

期刊论文

作者：

Li, Y.;Luo, H. B.;Zhang, H. Y.;Guo, Q.;Yao, H. C.;...

通讯作者：

Liu, Z. G.;Ye, X.

作者机构：

[Li, Y.; Liu, Z. G.] Wuhan Polytech Univ, Sch Biol & Pharmaceut Engn, Wuhan 430023, Peoples R China.

[Yang, J. G.; Wang, F.; Ye, X.; Luo, H. B.] Sichuan Univ Sci & Engn, Coll Bioengn, Liquor Marking Biol Technol & Applicat Key Lab Si, Zigong 643000, Peoples R China.

[Guo, Q.; Zhang, H. Y.; Li, J. Q.; Yang, X.; Yao, H. C.] Cent China Normal Univ, Coll Life Sci, Sect Environm Biomed, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.

[Chang, Q.] Hong Kong Univ Sci & Technol, Dept Chem & Biomol Engn, Hong Kong, Hong Kong, Peoples R China.

[Wang, C. D.] Sichuan Univ Arts & Sci, Dazhou 635000, Peoples R China.

通讯机构：

[Liu, Z. G.] W

[Ye, X.] S

Wuhan Polytech Univ, Sch Biol & Pharmaceut Engn, Wuhan 430023, Peoples R China.

Sichuan Univ Sci & Engn, Coll Bioengn, Liquor Marking Biol Technol & Applicat Key Lab Si, Zigong 643000, Peoples R China.

语种：

英文

期刊：

RSC Advances

ISSN：

2046-2069

年：

2016

卷：

期：

页码：

31122-31130

DOI：

10.1039/c5ra25750f

基金类别：

Open Research Fund of the Key Laboratory of Sichuan Province of China [NJ2011-01]; Talent Foundation of Sichuan University of Science Engineering [2015RC13]; Innovation and Entrepreneurship Students Training Project of Sichuan Province of China [201510622015]

机构署名：

本校为第一且通讯机构

院系归属：

生命科学与技术学院

摘要：

The free radical scavenging ability of fullerenols is their most exploited property in biomedical studies. The antioxidant properties and associated mechanisms of fullerenol have been previously investigated, but less research has been done to examine the hepatoprotective effects of fullerenol nanoparticles on alcohol-induced oxidative stress. This study examined the antioxidant effects in rat liver primary hepatocyte exposure to fullerenols dissolved in ethanol. In this study, liver primary hepatocytes of Wistar rats were divided into nine experimental groups that were exposed to ethanol (0.1...

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Potential hepatoprotective effects of fullerenol nanoparticles on alcohol-induced oxidative stress by ROS

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