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Naphthalimide‐based Functional Glycopolymeric Nanoparticles as Fluorescent Probes for Selective Imaging of Tumor Cells

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成果类型:
期刊论文
作者:
Li, Yi;Cai, Zhi;Gu, Jieyu;Chen, Jinghua*;Zhang, Yan
通讯作者:
Chen, Jinghua;Zhang, Y
作者机构:
[Chen, Jinghua; Gu, Jieyu; Cai, Zhi; Zhang, Yan; Li, Yi; Zhang, Y] Jiangnan Univ, Sch Life Sci & Hlth Engn, Key Lab Carbohydrate Chem & Biotechnol, Minist Educ, Wuxi 214122, Peoples R China.
[Cai, Zhi] Wuhan Polytech Univ, Sch Life Sci & Technol, Wuhan 430023, Peoples R China.
通讯机构:
[Chen, JH; Zhang, Y ] J
Jiangnan Univ, Sch Life Sci & Hlth Engn, Key Lab Carbohydrate Chem & Biotechnol, Minist Educ, Wuxi 214122, Peoples R China.
语种:
英文
关键词:
Glycopolymers;aggregation-induced emission;fluorescent probe;nanoparticles;tumor cell imaging
期刊:
CHEMISTRY-A EUROPEAN JOURNAL
ISSN:
0947-6539
年:
2024
卷:
30
期:
17
页码:
e202304165
基金类别:
National Natural Science Foundation of China; National Key Research and Development Program of China [2021YFC2103100]; Natural Science Foundation of Jiangsu Province [BK20180625]; [22008090]
机构署名:
本校为其他机构
摘要:
Naphthalimide‐based glycopolymeric nanoparticles with dual tumor‐targeting ability from glucose‐segment and phenylboronic ester modification were designed and used as pH sensitive and AIEgen fluorescent probes for selective imaging of tumor cells. Abstract A series of functional glycopolymer nanoparticles with 1,8‐naphthalimide motif was designed, synthesized and applied for tumor cell imaging. With the pH‐sensitive and aggregation‐induced emission (AIE) effect of the 1,8‐naphthalimide fluorescent probe, the presence of glucose‐based gl...

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