期刊论文

Study on Anti-inflammatory Effect Mechanism of Panax Japonicus Based on Network Pharmacology and Molecular Docking Technology

中文

科学与信息化

2096-2908

2023

15

164-168

本校为第一机构

利用TCMSP数据库获取竹节参的活性成分,GeneCards、OMIM和TTD数据库收集炎症相关靶点;采用Cytoscape、STRING等软件构建竹节参活性成分-靶点互作网络图;运用Autodock vina软件进行分...展开更多 利用TCMSP数据库获取竹节参的活性成分,GeneCards、OMIM和TTD数据库收集炎症相关靶点;采用Cytoscape、STRING等软件构建竹节参活性成分-靶点互作网络图;运用Autodock vina软件进行分子对接验证;利用David数据库进行GO、KEGG分析。筛选得到竹节参关键活性成分8个,核心靶点5个;分子对接验证结果表明关键活性成分与核心靶点结合稳定。富集到生物过程(BP)385条、分子功能(MF)96条、细胞组分(CC)47条;KEGG通...

TCMSP database is used to obtain the active components of Panax japonicus,and GeneCards,OMIM and TTD databases are used to collect inflammation-related targets.Cytoscape,STRING and other software are used to construct the Panax japonicus active component-target interact...MORE TCMSP database is used to obtain the active components of Panax japonicus,and GeneCards,OMIM and TTD databases are used to collect inflammation-related targets.Cytoscape,STRING and other software are used to construct the Panax japonicus active component-target interaction network diagram.Autodock vina software is used f...