期刊论文

Zhang, Juntao;Wang, Haibo

英文

Macromolecular Research

1598-5032

2020

28

6

636-643

10.1007/s13233-020-8077-1

Acknowledgments This study was financially supported by the National Natural Science Foundation of China (No. 21706201, No. 21676208, No. 21376183), Wuhan Application Basic Frontier Project (No. 2019020701011478), Wuhan Morning Light Plan of Youth Science and Technology (No. 2017050304010326), Hubei Provincial Natural Science Foundation of China (No. 2018CFA030, 2019CFB252), and Innovation Team Program of Hubei province, China (No. T201208).

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Modification of protein could give their new functionality but would affect their intrinsic property and activity. In this paper, a series of succinylated collagen (SCol(n/1)) (n≥1) were prepared by modification of collagen with succinic anhydride at different molar ratio to amino groups amount of collagen. The impact of grafting density on the intrinsic self-assembly and additional hydrophilicity of succinylated collagen was explored. The results revealed that excessive grafting density of succinylated collagen would improve their hydrophilic...