期刊论文

Synthesis of molecularly imprinted microspheres of α-tocopherol and evaluation of their absorption property

中文

食品安全质量检测学报

2095-0381

2015

3

843-850

10.19812/j.cnki.jfsq11-5956/ts.2015.03.021

湖北省教育厅青年项目（Q20121807）； 国家自然科学基金项目（31371783）； 国家局粮食公益性行业科研专项（2013007）~~；

本校为第一机构

目的采用沉淀聚合法制备α-生育酚分子印迹微球及条件优化,并对其吸附性能进行评价。方法以α-生育酚为印迹分子,甲基丙烯酸为功能单体,乙二醇二甲基丙烯酸酯为交联剂,偶氮二异丁腈为引发剂,在乙腈溶液中用沉淀聚合法合成了α-生育酚分子印迹聚合物微球,采用扫描电镜观察聚合物的形貌特征,并对影响其形貌的因素进行优化。结果最佳合成条件为:乙腈为反应溶剂,反应温度为60℃,模板用量为0.20mmol,引发剂用量为40 mg,转速为100 r/min。静态吸附试验结果表明,α-生育酚分子印迹聚合物微球具有两种不同的结合位点,结合位点的平衡吸附常数和最大平衡结合量分别为Kd1=0.995 mmol/L,Qmax1=22.420μmol/g...

Objective To prepare molecularly imprinted polymer (MIP) microspheres ofα-tocopherol by precipitation polymerization and the conditions optimization, moreover, the products absorption property were evaluated. Methods The MIPs of α-tocopherol were synthesized by precipitation polymerization by using methacrylic acid (MAA) and ethylene glycol dimethacrylate (EGDMA) and acetonitrile as functional monomer, cross-liker and solution, respectively. The morphology of the MIP microspheres was characterized by scanning electron microscope (SEM) and the...