Protective role of n6/n3 PUFA supplementation with varying DHA/EPA ratios against atherosclerosis in mice

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Liu, Liang;Hu, Qinling;Wu, Huihui;Xue, Yihong;Cai, Liang;...

通讯作者：

Gong, Zhiyong

作者机构：

[Cai, Liang; Wu, Huihui; Gong, Zhiyong; Liu, Liang; Wu, Yongning; Hu, Qinling; Xue, Yihong; Fang, Min] Wuhan Polytech Univ, Coll Food Sci & Engn, 68 XueFuNan Rd, Wuhan 430023, Peoples R China.

[Cai, Liang; Wu, Huihui; Gong, Zhiyong; Liu, Liang; Wu, Yongning; Liu, Zhiguo; Hu, Qinling; Xue, Yihong; Fang, Min] Wuhan Polytech Univ, Hubei Collaborat Innovat Ctr Proc Agr Prod, Wuhan 430023, Peoples R China.

[Liu, Zhiguo] Wuhan Polytech Univ, Sch Biol & Pharmaceut Engn, Wuhan 430023, Peoples R China.

[Yao, Ping] Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Nutr & Food Hyg, Sch Publ Hlth, Wuhan 430030, Peoples R China.

通讯机构：

[Gong, Zhiyong] W

Wuhan Polytech Univ, Coll Food Sci & Engn, 68 XueFuNan Rd, Wuhan 430023, Peoples R China.

语种：

英文

关键词：

*Alpha-linolenic acid;*Atherosclerosis;*DHA/EPA;*Docosahexaenoic acid;*Eicosapentaenoic acid;*n3 PUFA

期刊：

JOURNAL OF NUTRITIONAL BIOCHEMISTRY

ISSN：

0955-2863

年：

2016

卷：

页码：

171-180

DOI：

10.1016/j.jnutbio.2016.02.010

基金类别：

National High-tech Research and Development ProjectsNational High Technology Research and Development Program of China [2010AA023003]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31201351, 31271855]; Hubei Province Natural Science Foundation of ChinaNatural Science Foundation of Hubei Province [2013CFB481]

机构署名：

本校为第一且通讯机构

院系归属：

食品科学与工程学院

生命科学与技术学院

摘要：

The effects of n3 polyunsaturated fatty acids (PUFA) on cardiovascular disease are controversial. We currently explored the effects of various ratios of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) on high-fat-induced atherosclerosis. In model apoE(-/-) mice, high-fat diets (HFD) were partially replaced with fish and algal oils (DHA/EPA 2:1, 1:1 and 1:2) and/or plant oils enriched in linoleic and alpha-linolenic acids with an n6/n3 ratio of 4:1. PUFA supplementation significantly reduced the atherosclerotic plaque area, serum lipid profile, inflammatory response, aortic ROS produ...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Protective role of n6/n3 PUFA supplementation with varying DHA/EPA ratios against atherosclerosis in mice

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问