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Effects of Baicalin on piglet monocytes involving PKC-MAPK signaling pathways induced by Haemophilus parasuis.

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成果类型:
期刊论文
作者:
Ye, Chun;Li, Ruizhi;Xu, Lei;Qiu, Yinsheng*;Fu, Shulin;...
通讯作者:
Qiu, Yinsheng
作者机构:
[Ye, Chun; Li, Ruizhi; Xu, Lei; Qiu, Yinsheng; Fu, Shulin; Liu, Yu; Wu, Zhongyuan; Hou, Yongqing] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Hubei, Peoples R China
[Ye, Chun; Qiu, Yinsheng; Fu, Shulin; Liu, Yu; Wu, Zhongyuan; Hou, Yongqing] Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Wuhan 430023, Hubei, Peoples R China
[Hu, Chien-An Andy] Univ New Mexico, Sch Med, Biochem & Mol Biol, Albuquerque, NM 87131 USA
通讯机构:
[Qiu, Yinsheng] W
[Qiu, Yinsheng] H
Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Hubei, Peoples R China. Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Wuhan 430023, Hubei, Peoples R China.
语种:
英文
关键词:
Apoptosis;Baicalin;Glasser's disease;Haemophilus parasuis;PKC-MAPK
期刊:
BMC Veterinary Research
ISSN:
1746-6148
年:
2019
卷:
15
期:
1
页码:
1-11
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31572572]
机构署名:
本校为第一且通讯机构
院系归属:
动物科学与营养工程学院
摘要:
BACKGROUND: Haemophilus parasuis (HPS) is the causative agent of Glasser's disease, characterized by arthritis, fibrinous polyserositis and meningitis, and resulting in worldwide economic losses in the swine industry. Baicalin (BA), a commonly used traditional Chinese medication, has been shown to possess a series of activities, such as anti-bacterial, anti-viral, anti-tumor, anti-oxidant and anti-inflammatory activities. However, whether BA has anti-apoptotic effects following HPS infection is unclear. Here, we investigated the anti-apoptotic effects and mechanisms of BA in HPS-induced apopto...

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