The effects of baicalin on piglets challenged withGlaesserella parasuis

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成果类型：

期刊论文

作者：

Fu, Shulin;Yin, Ronghua;Zuo, Sanling;Liu, Jun;Zhang, Yunfei;...

通讯作者：

Qiu, Yinsheng

作者机构：

[Zhang, Yunfei; Hu, Chien-An Andy; Yin, Ronghua; Liu, Yu; Hou, Yongqing; Zuo, Sanling; Ye, Chun; Qiu, Yinsheng; Wu, Zhongyuan; Fu, Shulin; Liu, Jun; Guo, Ling] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Peoples R China.

[Zhang, Yunfei; Yin, Ronghua; Liu, Yu; Hou, Yongqing; Zuo, Sanling; Ye, Chun; Qiu, Yinsheng; Wu, Zhongyuan; Fu, Shulin; Liu, Jun; Guo, Ling] Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Wuhan 430023, Peoples R China.

[Hu, Chien-An Andy] Univ New Mexico, Sch Med, Biochem & Mol Biol, Albuquerque, NM 87131 USA.

通讯机构：

[Qiu, Yinsheng] W

[Qiu, Yinsheng] H

Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Peoples R China.

Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Wuhan 430023, Peoples R China.

语种：

英文

关键词：

baicalin;Glaesserella parasuis;piglets;inflammatory response;protection

期刊：

VETERINARY RESEARCH

ISSN：

0928-4249

年：

2020

卷：

期：

页码：

1-11

DOI：

10.1186/s13567-020-00826-5

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31572572]

机构署名：

本校为第一且通讯机构

院系归属：

动物科学与营养工程学院

摘要：

Glaesserella parasuis (G. parasuis) causes porcine vascular inflammation and damage. Baicalin is reported to have antioxidant and anti-inflammatory functions. However, whether baicalin protects piglets against G. parasuis challenge and the potential protective mechanism have not been investigated. Therefore, in this study, we comprehensively examined the protective efficacy of baicalin in piglets challenged with G. parasuis and the possible protective mechanism. Our results show that baicalin attenuated the release of the inflammation-related c...

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The effects of baicalin on piglets challenged withGlaesserella parasuis

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