期刊论文

Wei, Wei;Zhou, Dao-Xiu

英文

分子植物

1674-2052

2017

10

12

1510-1522

10.1016/j.molp.2017.10.010

National Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31600981]; Hubei Provincial Department of Education Scientific Research Plan Guidance Project [B2016297]

本校为其他机构

How plant metabolic flux alters gene expression to optimize plant growth and response to stress remains largely unclear. Here, we report that Arabidopsis thaliana NAD~+-dependent histone deacetylase AtSRT1 negatively regulates plant tolerance to stress and glycolysis but stimulates mitochondrial respiration. We found that AtSRT1 interacts with Arabidopsis cMyc-Binding Protein 1 (AtMBP-1), a transcriptional repressor produced by alternative translation of the cytosolic glycolytic enolase gene LOS2/ENO2. We demonstrated that AtSRT1 could associate with the chromatin of AtMBP-1 targets LOS2/ENO2 ...

怎么种新陈代谢的流动，改变基因表示优化植物生长，对应力的反应仍然保持大部分不清楚。这里，我们报导 Arabidopsis thaliana NAD +-dependent histone deacetylase AtSRT1 否定地调整植物公差到应力和 glycolysis，但是刺激 mitochondrial 呼吸。我们发现 AtSRT1 与 Arabidopsis cMyc 有约束力的蛋白质 1 交往(AtMBP-1 ) ，一个 transcriptional 抑压者由 cytosolic glycolytic enolase 基因 LOS2/ENO2 的其他的翻译生产了。我们证明 AtSRT1 能与 AtMBP-1 目标 LOS2/ENO2 和 STZ/ZAT10 的染色质联系，哪个编码关键压力管理者，并且在这些基因减少 H3K9ac 层次镇压他们的抄写。AtSRT1 和 AtMB...