Flax Lignans modulate the digestion and absorption of α-linolenic acid in sunflower phospholipid-stabilized nanoemulsions: In vitro digestion simulation and in vivo studies in mice

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期刊论文

作者：

Wang, Lei;Yu, Xiao;Cheng, Chen;Xu, Jiqu;Xiang, Xia;...

通讯作者：

Chen, Li;Deng, QC

作者机构：

[Deng, Qianchun; Wang, Lei; Yu, Xiao; Xiang, Xia; Chen, Li; Xu, Jiqu] Chinese Acad Agr Sci, Oil Crops Res Inst, Hubei Key Lab Lipid Chem & Nutr, Wuhan 430062, Hubei, Peoples R China.

[Deng, Qianchun; Wang, Lei; Yu, Xiao; Xiang, Xia; Chen, Li; Xu, Jiqu] Minist Agr, Key Lab Oilseeds Proc, Oil Crops & Lipids Proc Technol Natl & Local Joint, Wuhan 430062, Hubei, Peoples R China.

[Yu, Xiao] Zhengzhou Univ Light Ind, Coll Food & Bioengn, Zhengzhou 450001, Henan, Peoples R China.

[Cheng, Chen] Wuhan Polytech Univ, Sch Modern Ind Selenium Sci & Engn, Wuhan 430023, Hubei, Peoples R China.

[Tang, Xiaoqiao] Hubei Prov Ctr Dis Control & Prevent, Wuhan 430079, Hubei, Peoples R China.

通讯机构：

[Deng, QC ; Chen, L] C

Chinese Acad Agr Sci, Oil Crops Res Inst, Wuhan 430062, Hubei, Peoples R China.

语种：

英文

关键词：

Bioavailability;Digestion and absorption;Flax lignans;Nanoemulsions;α-Linolenic acid

期刊：

Food Research International

ISSN：

0963-9969

年：

2025

卷：

220

页码：

117049

DOI：

10.1016/j.foodres.2025.117049

基金类别：

National Natural Science Foundation of China [32072267]; Earmarked fund [CARS-14]; National Key Research and Development Program of China [2023YFD2100404]; Innovation Group Project of Hubei Province [2023AFA042]

机构署名：

本校为其他机构

院系归属：

硒科学与工程现代产业学院

摘要：

Dietary supplementation with plant-derived α-linolenic acid (ALA), relying on its metabolic conversion into n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFAs), has the potential to optimize the dietary fatty acid profile and alleviate the global issue of insufficient n-3 LCPUFAs intake. Current research investigates the effects of flax lignans, with varying doses and structures, on the intestinal digestion-absorption and lymph-blood transport of ALA in sunflower phospholipid-stabilized nanoemulsions. The results indicated that the incorp...

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Flax Lignans modulate the digestion and absorption of α-linolenic acid in sunflower phospholipid-stabilized nanoemulsions: In vitro digestion simulation and in vivo studies in mice

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