期刊论文

中文

食品科学

1002-6630

2006

27

3

210-212

10.3321/j.issn:1002-6630.2006.03.050

教育部2002年度博士点基金资助项目（20020504008） 湖北省科技攻关项目（2003AA20412307）.

本校为其他机构

本文研究了菹草类胡萝卜素（CEPC）的抗癌作用及其对免疫功能的影响。以动物移植性肿瘤小鼠肝癌H22为模型，以环磷酰胺为阳性对照，以色拉油为阴性对照，舰察5、10、20mg／kg·d的CEPC的体内抗肿瘤作用及其对荷瘤小鼠肝脏中MDA、SOD的影响，通过CEPC对二硝基氟苯（DNFB）诱导的迟发型变态反应（DTH），对淋巴细胞增殖反应的作用和NK细胞活性的测定来观察其对免疫系统的影响。结果表明低中高浓度的CEPC与阴性对照组相比对肝癌H22瘤细胞均有较强的杀伤力，对荷瘤小鼠肝脏中MDA有降低作用，对SOD有增强作用，且CEPC对小鼠免疫系统具有较强的激活作用。提示CEPC对移植性H22肿瘤小鼠具有抗肿瘤作用，...

The antitumor activity and immune function of carotenoids from Potamogeton crispus L. （CEPC） were studied in this article. Cyclophosphamide was the positive control and salad oil the negative control. H22-bearing mice were used as animal models. The changes of H22 tumor weight in vivo, the changes of MDA and SOD of liver in H22-bearing mice and the effect on immune system such as DTH induced by DNFB, proliferation of lymphocytes and NK activity were investigated when different dosage CEPC （5, 10, 20mg/kg·d） were used. It was shown that CEP...