期刊论文

中文

食品科学

1002-6630

2011

32

15

269-272

本校为第一机构

以成年SD大鼠为实验材料,采用D-半乳糖连续腹腔注射制作亚急性衰老的大鼠模型,造模成功后连续灌胃蜂王浆,运用Morris水迷宫观察各组大鼠的空间学习记忆行为;荧光分光光度法检测各组大鼠脑组织中单胺类神经递质去甲肾上腺素(NE)、多巴胺(DA)的含量;检测各组大鼠脑组织中超氧化物歧化酶(SOD)活性、丙二醛 (M DA)含量。结果显示:D-半乳糖衰老模型大鼠的空间学习记忆能力明显下降,与正常组大鼠相比,潜伏期由15.52s延长至21.62s,在探索实验中,穿过原站台的次数明显减少,由7.5次减少至4.25次(P＜0.05),游泳轨迹类型发生明显变化;与正常组相比模型大鼠脑组织中NE、DA含量显著降低,SOD活性显著降低,MDA含...

Adult SD rats were used as experimental subjects to establish a subacute aging model by intraperitoneally injecting D-galactose.After the aging model was successfully established,the aged rats were administered intragastrically with royal jelly.The learning and memory of the rats in each group were evaluated by Morris water maze.The contents of monoamine transmitters such as norepinephrine（NE） and dopamine（DA） in the brain tissue were determined in a fluorescence spectrophotometer.Meanwhile,cerebral SOD activity and DNA content in the rats ...