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Effects of Vitamin A on Immune Responses and Vitamin A Metabolism in Broiler Chickens Challenged with Necrotic Enteritis

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成果类型:
期刊论文
作者:
Guo, Shuangshuang;He, Lai;Zhang, Yuanke;Niu, Junlong;Li, Changwu;...
通讯作者:
Ding, BY
作者机构:
[Zhang, Yuanke; Zhang, Zhengfan; Ding, Binying; Guo, Shuangshuang; Li, Changwu; He, Lai; Li, Peng; Niu, Junlong] Wuhan Polytech Univ, Engn Res Ctr Feed Prot Resources Agr By Prod, Hubei Key Lab Anim Nutr & Feed Sci, Minist Educ, Wuhan 430023, Peoples R China.
通讯机构:
[Ding, BY ] W
Wuhan Polytech Univ, Engn Res Ctr Feed Prot Resources Agr By Prod, Hubei Key Lab Anim Nutr & Feed Sci, Minist Educ, Wuhan 430023, Peoples R China.
语种:
英文
关键词:
vitamin A;retinoic acid;necrotic enteritis;immune response;metabolism;broiler chicken
期刊:
Life
ISSN:
2075-1729
年:
2023
卷:
13
期:
5
页码:
1122-
基金类别:
Conceptualization, S.G. and B.D.; methodology, L.H., Y.Z. and J.N.; software, S.G. and L.H.; validation, Z.Z., and P.L.; formal analysis, S.G., Z.Z. and B.D.; investigation, S.G., L.H., Y.Z. and J.N.; resources, Z.Z.; data curation, S.G., C.L. and Z.Z.; writing—original draft preparation, S.G. and L.H.; writing—review and editing, C.L., Z.Z., P.L. and B.D.; visualization, Y.Z. and J.N.; supervision, B.D.; project administration, S.G. and B.D.; funding acquisition, S.G. and B.D. All authors have read and agreed to the published version of the manuscript. This research was funded by the National Natural Science Foundation of China (No. 32172757), the National Key R&D Program of China (No. 2016YFD0501202), the National Science Foundation of Hubei Province (2021CFB559) and the Open Project of Hubei Key Laboratory of Animal Nutrition and Feed Science (No. 201902).
机构署名:
本校为第一且通讯机构
院系归属:
动物科学与营养工程学院
摘要:
Necrotic enteritis (NE) is an important enteric inflammatory disease of poultry, and the effects of vitamin A (VitA) on NE birds are largely unknown. The present study was conducted to investigate the effects of VitA on the immune responses and VitA metabolism of NE broilers as well as the underlying mechanisms. Using a 2 x 2 factorial arrangement, 336 1-day-old Ross 308 broiler chicks were randomly assigned to 4 groups with 7 replicates. Broilers in the control (Ctrl) group were fed a basal diet without extra VitA supplementation. Broilers in the VitA group were fed a basal diet supplemented ...

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