Aldehyde dehydrogenase 2(ALDH2)is one of important factors against from the damage under oxidative stress in human body.A high proportion of East Asians carry ALDH2 inactive mutation gene.There are many diseases closely related to ALDH2,such as cardiovascular diseases,neurodegenerative diseases and liver diseases.Recent studies also have found that ALDH2 is associated with ferroptosis.Therefore,ALDH2 has becoming a potential target for the treatment of the above related diseases.Several types of small molecule activators with potential value of clinical application have been reported.The resea...
