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Fine and ultrafine airborne PM influence inflammation response of young adults and toxicological responses in vitro

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成果类型:
期刊论文
作者:
Yang, Mo;Jalava, Pasi;Hakkarainen, Henri;Roponen, Marjut;Leskinen, Ari;...
通讯作者:
Guang-Hui Dong
作者机构:
[Jalava, Pasi; Roponen, Marjut; Yang, Mo; Hakkarainen, Henri] Univ Eastern Finland, Dept Environm & Biol Sci, Yliopistonranta 1,1627, FI-70211 Kuopio, Finland.
[Yang, Bo-Yi; Wu, Qi-Zhen; Hu, Li-Wen; Liu, Ru -Qing; Xu, Shu-Li; Yang, Mo; Dong, Guang-Hui; Zeng, Xiao-Wen; Lin, Li-Zi] Sun Yat sen Univ, Guangdong Prov Engn Technol Res Ctr Environm Pollu, Sch Publ Hlth, Dept Occupat & Environm Hlth, Guangzhou 510080, Peoples R China.
[Leskinen, Ari; Komppula, Mika] Finnish Meteorol Inst, Yliopistonranta 1,1627, FI-70211 Kuopio, Finland.
[Leskinen, Ari] Univ Eastern Finland, Dept Appl Phys, Yliopistonranta 1,1627, FI-70211 Kuopio, Finland.
[Dong, Guo -Ping] Guangzhou Huashang Coll, Dept Accounting, Guangzhou, Peoples R China.
通讯机构:
[Guang-Hui Dong] G
Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, 74 Zhongshan 2nd Road, Yuexiu District, Guangzhou, China
语种:
英文
关键词:
Airborne PM;Young adults;Toxicological responses;Inflammation response
期刊:
Science of The Total Environment
ISSN:
0048-9697
年:
2022
卷:
836
页码:
155618
基金类别:
National Key Research and Development Program of China [2018YFE0106900]; National Natural Science Foundation of China [M-0420, 82130094, 82173471, 82073502, 81872582, 81872583]; Guangdong Provincial Natural Science Foundation Team Project [2018B030312005]; Natural Science Foundation of Guangdong Province [2021B1515020015, 2021A1515011754, 2020A1515011131, 2019A050510017, 2018B050-52007, 2017A090905042]; Academy of Finland [319245, 294081, 287982]; Transport Derived Ultrafines and the Brain Effects [814978]
机构署名:
本校为其他机构
摘要:
Little evidence is available regarding the impact of different sizes of inhaled particulate matter (PM) on inflammatory responses in healthy young adults in connection with toxicological responses. We conducted a five-time repeated measurement panel study on 88 healthy young college students in Guangzhou, China from December 2017 to January 2018. Blood samples were collected from each participant and tested for tumor necrosis factor alpha (TNF-α) levels every week for 5 consecutive weeks. Mass concentrations of ambient PM(2.5), PM(1), PM(0.5) ...

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