Ferroptosis in Liver Disease: Natural Active Compounds and Therapeutic Implications

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成果类型：

期刊论文

作者：

Wu, Zhili;Zhu, Yanru;Liu, Wenchao;Balasubramanian, Balamuralikrishnan;Xu, Xiao;...

通讯作者：

Lei, XJ

作者机构：

[Lei, Xinjian; Zhu, Yanru; Yao, Junhu; Wu, Zhili; Lei, XJ] Northwest A&F Univ, Coll Anim Sci & Technol, Yangling 712100, Peoples R China.

[Lei, Xinjian; Zhu, Yanru; Yao, Junhu; Wu, Zhili; Lei, XJ] Northwest A&F Univ, Key Lab Livestock Biol, Yangling 712100, Peoples R China.

[Liu, Wenchao] Guangzhou Ocean Univ, Coll Coastal Agr Sci, Zhanjiang 524088, Peoples R China.

[Balasubramanian, Balamuralikrishnan] Sejong Univ, Dept Food Sci & Biotechnol, Coll Life Sci, Seoul 05006, South Korea.

[Xu, Xiao] Wuhan Polytech Univ, Sch Anim Sci & Nutr Engn, Wuhan 430023, Peoples R China.

通讯机构：

[Lei, XJ ] N

Northwest A&F Univ, Coll Anim Sci & Technol, Yangling 712100, Peoples R China.

Northwest A&F Univ, Key Lab Livestock Biol, Yangling 712100, Peoples R China.

语种：

英文

关键词：

ferroptosis;natural active compounds;liver disease;therapeutic implications

期刊：

Antioxidants

ISSN：

2076-3921

年：

2024

卷：

期：

页码：

352-

DOI：

10.3390/antiox13030352

基金类别：

This research was funded by National Natural Science Foundation of China (32102569) and the Science & Technology Projects of Shaanxi Province (2023KJXX-132; 2022ZDLNY01-09; 2022GD-TSLD-46-0501; 2022QFY11-05).

机构署名：

本校为第一机构

院系归属：

动物科学与营养工程学院

摘要：

Ferroptosis is an emerging type of regulated cell death usually accompanied by the accumulation of ferrous ions (Fe2+) and lipid peroxides. As the metabolic hub of the body, the liver is crucial for iron storage and lipid metabolism. The liver seems to be closely related to ferroptosis through iron and lipid metabolism. Liver disease greatly threatens host health, and exploring effective interventions is essential. Mounting studies have demonstrated that ferroptosis is one of the possible pathogenic mechanisms involved in liver disease. Targeting ferroptosis may provide a promising opportunity...

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Ferroptosis in Liver Disease: Natural Active Compounds and Therapeutic Implications

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