The authors acknowledge the generous funding from the excellent young and middle-aged scientific and technological innovation teams in colleges and universities of Hubei Province under Grant T2021009.; excellent young and middle-aged scientific and technological innovation teams in colleges and universities of Hubei Province; [T2021009]
机构署名：
本校为第一且通讯机构
院系归属：
数学与计算机学院
医学与健康学院
摘要：
Background: Migraine is a common neurovascular disorder with typical throbbing and unilateral headaches, causing a considerable healthcare burden on the global economy. This research aims to prepare chitosan-alginate (CS-AL) nanoparticles (NPs) containing Foshousan oil (FSSO) and investigate its potential therapeutic effects on the treatment of migraine.Methods: FSSO-loaded CS-AL NPs were prepared by using the single emulsion solvent evaporation method. Lipopolysaccharide (LPS)-stimulated BV-2 cells and nitroglycerin (NTG)-induced migraine mice were further used to explore anti-migraine activi...
