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Biofabrication of a novel biomolecule-assisted reduced graphene oxide: an excellent biocompatible nanomaterial

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成果类型:
期刊论文
作者:
Zhang, Xi-Feng;Gurunathan, Sangiliyandi*
通讯作者:
Gurunathan, Sangiliyandi
作者机构:
[Zhang, Xi-Feng] Wuhan Polytech Univ, Coll Biol & Pharmaceut Engn, Wuhan, Peoples R China.
[Gurunathan, Sangiliyandi] Konkuk Univ, Dept Stem Cell & Regenerat Biotechnol, Seoul 143701, South Korea.
通讯机构:
[Gurunathan, Sangiliyandi] K
Konkuk Univ, Dept Stem Cell & Regenerat Biotechnol, Seoul 143701, South Korea.
语种:
英文
关键词:
biocompatibility;graphene oxide;nicotinamide;reduced graphene oxide;tight junction proteins;alkaline phosphatase
期刊:
INTERNATIONAL JOURNAL OF NANOMEDICINE
ISSN:
1178-2013
年:
2016
卷:
11
页码:
6635-6649
基金类别:
KU-Research Professor Program of Konkuk University; Science and Technology Research Program of the Department of Education of Hubei Province, People's Republic of China [D20151701]
机构署名:
本校为第一机构
院系归属:
生命科学与技术学院
摘要:
Graphene has been shown much interest, both in academics and industry due to its extraordinary physical, chemical, and biological proprieties. It shows great promises in biotechnological and biomedical applications as an antibacterial and anticancer agent, nanocarrier, sensor, etc. However, many studies demonstrated the toxicity of graphene in several cell lines, which is an obstacle to its use in biomedical applications. In this study, to improve the biocompatibility of graphene, we used nicotinamide (NAM) as a reducing and stabilizing agent to catalyze the reduction of graphene oxide (GO) to...

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