Phenotypic and molecular characterisation of a novel species, Mycobacterium hubeiense sp., isolated from the sputum of a patient with secondary tuberculosis in Hubei of China

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成果类型：

期刊论文

作者：

Yu, Xiaoli;Zheng, Hui;Zhou, Fang;Hu, Peng;Wang, Hualin;...

通讯作者：

Zhang, Shulin;Xiang, Jie

作者机构：

[Wang, Hualin; Wang, Peidong; Zhang, Lu; Hu, Peng; He, Juncai; Yu, Xiaoli; Li, Na; Zheng, Hui; Zhou, Fang] Wuhan Polytech Univ, Sch Biol & Pharmaceut Engn, Wuhan, Peoples R China.

[Zhang, Lu; Zhang, Shulin] Shanghai Jiao Tong Univ, Dept Immunol & Microbiol, Sch Med, Shanghai, Peoples R China.

[Xiang, Jie] Wuhan Med Treatment Ctr, Wuhan, Peoples R China.

[Men, Hongsheng] Univ Missouri, Dept Vet Pathobiol, Columbia, MO USA.

[Zhang, Shulin] Shanghai Publ Hlth Clin Ctr, TB Res Ctr, Shanghai, Peoples R China.

通讯机构：

[Zhang, Shulin] S

[Xiang, Jie] W

Shanghai Jiao Tong Univ, Dept Immunol & Microbiol, Sch Med, Shanghai, Peoples R China.

Wuhan Med Treatment Ctr, Wuhan, Peoples R China.

Shanghai Publ Hlth Clin Ctr, TB Res Ctr, Shanghai, Peoples R China.

语种：

英文

关键词：

16S rRNA;genomic analysis;nontuberculous mycobacteria;phenotype;rpoB

期刊：

Epidemiology and Infection

ISSN：

0950-2688

年：

2020

卷：

148

页码：

1-18

DOI：

10.1017/S0950268820000436

基金类别：

National Science and Technology Major Project of China [2017ZX10201301-003-001, 2017ZX10201301-003-003]; China National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81871613]

机构署名：

本校为第一机构

院系归属：

生命科学与技术学院

摘要：

Abstract A new fast-growing mycobacterium, designated strain QGD101T, was isolated from the sputum of an 84-year-old man suspected of tuberculosis in Wuhan Medical Treatment Center, Hubei, China. This strain was a gram-staining-negative, aerobic, non-spore-forming and catalase-positive bacterium, which was further identified as the NTM by PNB and TCH tests. The moxifloxacin and levofloxacin exhibited strong suppressing function against QGD101T with MIC values of 0.06 and 0.125 µg/ml after drug susceptibility testing of six main antimicrobial...

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Phenotypic and molecular characterisation of a novel species, Mycobacterium hubeiense sp., isolated from the sputum of a patient with secondary tuberculosis in Hubei of China

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