期刊论文

Shen, Wei

英文

Molecular Biology Reports

0301-4851

2013

40

11

6509-6517

10.1007/s11033-013-2769-y

National Nature Science FoundationNational Natural Science Foundation of China (NSFC) [31201120, 31000772]; Program for New Century Excellent Talents in University, Foundation of Distinguished Young Scholars [JQ201109]; Foundation of Education Department of Shandong Province [J11LC20]; Nature Science Foundation of Hubei ProvinceNatural Science Foundation of Hubei Province [2011CDB230]

本校为其他机构

We previously demonstrated that the effects of diethylhexyl phthalate (DEHP) alter reproduction function on male mice. Immature male mice were treated daily with DEHP from postnatal day 7-21, 7-35, 7-49, in a dose-dependent manner. As results, both the quality and quantity of spermatozoa were decreased in 60-day-old mice. The results by RT-PCR analysis indicated that DDx3Y, Usp9Y, RBM, E1F1AY, EGF, FSHR and EGFR genes were down-regulated, and LHR, Cyp17a1 and Cyp19a1 were down-regulated in response to DEHP. These genes were selected based on their markedly increased or decreased expression lev...