Catabolism and safety of supplemental l-arginine in animals

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Wu, Zhenlong;Hou, Yongqing;Hu, Shengdi;Bazer, Fuller W.;Meininger, Cynthia J.;...

通讯作者：

Wu, Guoyao

作者机构：

[Wu, Zhenlong; Wu, Guoyao] China Agr Univ, State Key Lab Anim Nutr, Beijing 100193, Peoples R China.

[Hou, Yongqing; Wu, Guoyao] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Wuhan 430023, Peoples R China.

[Bazer, Fuller W.; Hu, Shengdi; Wu, Guoyao] Texas A&M Univ, Dept Anim Sci, College Stn, TX 77843 USA.

[Meininger, Cynthia J.; Wu, Guoyao] Texas A&M Hlth Sci Ctr, Dept Med Physiol, Temple, TX 76504 USA.

[McNeal, Catherine J.] Baylor Scott & White Hlth, Dept Internal Med, Temple, TX 76508 USA.

通讯机构：

[Wu, Guoyao] C

[Wu, Guoyao] W

[Wu, Guoyao] T

China Agr Univ, State Key Lab Anim Nutr, Beijing 100193, Peoples R China.

Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Wuhan 430023, Peoples R China.

语种：

英文

关键词：

Amino acids;Nutrition;Catabolism;Health;Dietary supplementation

期刊：

Amino Acids

ISSN：

0939-4451

年：

2016

卷：

期：

页码：

1541-1552

DOI：

10.1007/s00726-016-2245-9

基金类别：

This work was supported by grants from International Council of Amino Acid Science (Brussels, Belgium), Texas A&M AgriLife Research (H-8200), National Basic Research Program of China (2012CB126305), National Natural Science Foundation of China (31172217 and 31272450), Natural Science Foundation of Hubei Province (2013CFA097 and 2013CFB325), and Hubei Hundred Talent program. We thank Drs. Robert Burghardt, Zhaolai Dai, Gregory Johnson, Xilong Li, Sidney Morris, and Stephen Smith for research collaboration.

机构署名：

本校为通讯机构

院系归属：

动物科学与营养工程学院

摘要：

l-arginine (Arg) is utilized via multiple pathways to synthesize protein and low-molecular-weight bioactive substances (e.g., nitric oxide, creatine, and polyamines) with enormous physiological importance. Furthermore, Arg regulates cell signaling pathways and gene expression to improve cardiovascular function, augment insulin sensitivity, enhance lean tissue mass, and reduce obesity in humans. Despite its versatile roles, the use of Arg as a dietary supplement is limited due to the lack of data to address concerns over its safety in humans. Da...

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Catabolism and safety of supplemental l-arginine in animals

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