Wu, Dingwei;Tao, Suwan;Zhu, Lian;Zhao, Chenchen;Xu, Na
作者机构:
[Tao, Suwan; Zhao, Chenchen; Xu, Na; Wu, Dingwei] Institute of Biology and Medicine, College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan 430065, China
[Zhu, Lian] School of Chemical and Environmental Engineering, Wuhan Polytechnic University, Wuhan 430023, China
[Zhao, Chenchen] School of Basic Medical Sciences, Jinzhou Medical University, Jinzhou 121000, China
Cutaneous trauma repair is still a challenge in the clinic due to the scar formation and slow healing rate, especially for diabetic patients. Various drug-loading wound dressings have been explored to solve this problem. Mesenchymal stem cell (MSC)-derived exosomes have been considered as a potential cell-free drug because of their anti-inflammation function and tissue repair property that are comparable to that of MSCs. Herein, a composite wound dressing (Exo/Gel) consisting of the chitosan hydrogel and adipose MSC-derived exosome (ADMSC-Exo) was designed and fabricated by a physical mixing m...