期刊论文

中文

中国医院药学杂志

1001-5213

2009

29

13

1082-1085

10.3321/j.issn:1001-5213.2009.13.007

本校为第一机构

目的:研究竹节参多糖的抗衰老作用.方法:将昆明种小鼠按体质量随机分组,分别给予生理盐水、D-半乳糖、香菇菌多糖、竹节参多糖.测定胸腺和脾脏指数,取血、肝、脑测定丙二醛、超氧化物歧化酶、谷胱甘肽过氧化物酶和过氧化氢酶.结果:竹节参多糖可以拮抗胸腺和脾脏萎缩,显著降低丙二醛含量并提高超氧化物歧化酶、谷胱甘肽过氧化物酶和过氧化氢酶活力.结论:竹节参多糖可通过小鼠调节机体免疫功能、清除自由基等方面发挥其延缓衰老的作用.

OKIECTIVE To study the anti-aging effect of polysaccharides from Panaxjaponicus in mice. METHODS Ran-dom groups were prepared by body and were given with NaC1 liquor, D-galactose, letinan and polysaccharides from Panax ja-ponicus. The activity of SOD and contents of MDA in serum of the mice were determined with UV. The activity of GSH-PX in liver and CAT in brain were measured too. Meanwhile, mice were weighted and thymus and spleen were taken out to weight with electronic balance. Wet mass of organs was used to express indexes of thymus and spleen so as to observe the effect on im-munological...