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Structural Characterization and Assessment of Anti-Inflammatory Activities of Polyphenols and Depsidone Derivatives from Melastoma malabathricum subsp. normale

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成果类型:
期刊论文
作者:
He, Rui-Jie;Wang, Ya-Feng;Yang, Bing-Yuan;Liu, Zhang-Bin;Li, Dian-Peng;...
通讯作者:
Huang, YL;Zou, BQ
作者机构:
[Huang, YL; Li, Dian-Peng; Liu, Zhang-Bin; Huang, Yong-Lin; Yang, Bing-Yuan; He, Rui-Jie; Wang, Ya-Feng] Guangxi Inst Bot, Guangxi Key Lab Plant Funct Phytochem & Sustainab, Guilin 541006, Guangxi Zhuang, Peoples R China.
[Huang, YL; Li, Dian-Peng; Liu, Zhang-Bin; Huang, Yong-Lin; Yang, Bing-Yuan; He, Rui-Jie; Wang, Ya-Feng] Chinese Acad Sci, Guilin 541006, Peoples R China.
[Zou, Bi-Qun] Guilin Normal Coll, Dept Chem, Gulin 541199, Peoples R China.
通讯机构:
[Huang, YL ; Zou, BQ ] G
Guangxi Inst Bot, Guangxi Key Lab Plant Funct Phytochem & Sustainab, Guilin 541006, Guangxi Zhuang, Peoples R China.
Chinese Acad Sci, Guilin 541006, Peoples R China.
Guilin Normal Coll, Dept Chem, Gulin 541199, Peoples R China.
语种:
英文
关键词:
Melastoma malabathricum subsp;normale (D;Don) Karst;Mey;Melastoma;polyphenols;complex tannin;depsidone derivatives;anti-inflammatory
期刊:
Molecules
ISSN:
1420-3049
年:
2022
卷:
27
期:
5
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [32060108, 82060764]; Natural Science Foundation of Guangxi ProvinceNational Natural Science Foundation of Guangxi Province [2018GXNSFAA294033]; Fundamental Research Fund of Guangxi Institute of Botany [GUIZHIYE 18004]; Guangxi Innovation-Driven Development Special Fund [GuiKe AA18118015]; Guangxi Key Laboratory of Plant Functional Phytochemicals [ZRJJ2020-2]; State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University [CMEMR2019-B13]; Key-Area Research and Development Program of Guangdong Province [2020B1111110003]; Program of Colleges and Universities in Guangxi [GUIKE 20111010]
机构署名:
本校为通讯机构
摘要:
The roots of Melastoma malabathricum subsp. normale (D. Don) Karst. Mey have been used in traditional ethnic medicine systems in China to treat inflammation-triggered ailments, such as trauma, toothache, and fever. Therefore, the aim of this study is to screen for compounds with anti-inflammatory activity in the title plant. The extract of M. malabathricum subsp. normale roots was separated using various chromatographic methods, such as silica gel, ODS C18, MCI gel, and Sephadex LH-20 column chromatography, as well as semi-preparative HPLC. One new complex tannin, named whiskey tannin D (1), a...

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