期刊论文

Hou, Yongqing

英文

FRONTIERS IN IMMUNOLOGY

1664-3224

2020

11

509407

10.3389/fimmu.2020.00169

This work was supported by the National Key R&D Program (grant number 2016YFD0501210), the Program of National Agricultural Research Outstanding Talents of China (2015), Hubei Provincial Key R&D Program (2019ABA083), Texas A&M AgriLife Research (H-8200), and the Open Project of Hubei Key Laboratory of Animal Nutrition and Feed Science (grant number 201805).

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Porcine epidemic diarrhea virus (PEDV) has caused enormous economic losses to the swine industry worldwide in recent years. Puerarin (PR), a major isoflavonoid isolated from the Chinese herb Gegen, possesses many pharmacological activities, including anti-inflammatory, and anti-viral activities. This study was conducted with both PEDV-infected African green monkey kidney cells (Vero) and neonatal pigs to determine the effect of PR on PEDV infection and to elucidate the underlying mechanisms by using proteomic analyses. Twenty-four piglets fed a...