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Stability analysis of a multi-layer tumor model with free boundary

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成果类型:
期刊论文
作者:
Hou, Xiumei*;Wu, Junde
通讯作者:
Hou, Xiumei
作者机构:
[Hou, Xiumei] Wuhan Polytech Univ, Sch Math & Comp Sci, Wuhan 430023, Hubei, Peoples R China.
[Wu, Junde] Soochow Univ, Dept Math, Suzhou 215006, Jiangsu, Peoples R China.
通讯机构:
[Hou, Xiumei] W
Wuhan Polytech Univ, Sch Math & Comp Sci, Wuhan 430023, Hubei, Peoples R China.
语种:
英文
关键词:
Free boundary problem;Tumor growth;Stability;Gibbs-Thomson relation
期刊:
Computers & Mathematics with Applications
ISSN:
0898-1221
年:
2019
卷:
77
期:
1
页码:
199-208
基金类别:
This work is financially supported by the DoctoralStarting up Foundation of Wuhan Polytechnic University , China. The authors would like to thank the anonymous referees and Professor Shangbin,Cui for their helpful comments and suggestion.
机构署名:
本校为第一且通讯机构
院系归属:
数学与计算机学院
摘要:
In this paper we study a multi-layer tumor model which is expressed as a free boundary problem of a system of partial differential equations. The problem consists of two elliptic equations describing the distribution of nutrient concentration and the pressure between tumor cells, respectively, in an unbounded strip-like region in which the tumor occupies. This region has two disjoint boundaries: While the lower part is fixed, the upper part, which stands for the tumor surface, can move as the tumor grows. Under certain conditions, the problem can be proved to admit a unique equilibrium which c...

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