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Pyruvate is an effective substitute for glutamate in regulating porcine nitrogen excretion

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成果类型:
期刊论文
作者:
Li, Yunxia;Tang, Zhiru;Li, Tiejun;Chen, C.;Huang, Feiruo;...
通讯作者:
Sun, Zhihong
作者机构:
[Li, Yunxia] Sichuan Agr Univ, Inst Anim Nutr, Chengdu 611130, Sichuan, Peoples R China.
[An, Rui; Sun, Jiajing; Zhen, Jifu; Wu, Zhaoliang; Li, Mao; Wu, Liuting; Sun, Zhihong; Li, Yunxia; Tang, Zhiru; Xu, Qingqing; Zhang, Xiangxin; Yang, Jing; Chen, Jinchao; Chen, C.] Southwest Univ, Coll Anim Sci & Technol, Lab Biofeed & Mol Nutr, Chongqing 400715, Peoples R China.
[Li, Tiejun; Yin, Yulong] Chinese Acad Sci, Inst Subtrop Agr, Changsha 410125, Hunan, Peoples R China.
[Huang, Feiruo] Huazhong Agr Univ, Coll Anim Sci & Technol, Wuhan 430070, Hubei, Peoples R China.
[Zhao, Shengjun] Wuhan Polytech Univ, Sch Anim Sci & Nutr Engn, Wuhan 430023, Hubei, Peoples R China.
通讯机构:
[Sun, Zhihong] S
Southwest Univ, Coll Anim Sci & Technol, Lab Biofeed & Mol Nutr, Chongqing 400715, Peoples R China.
语种:
英文
关键词:
alanine;amino acid;glutamic acid;nitrogen;pyruvic acid;urea;animal;animal food;cell line;cytology;diet;dietary supplement;drug effect;energy metabolism;epithelium cell;intestine mucosa;male;metabolism;oxidation reduction reaction;physiology;pig;protein intake;protein restriction;veterinary medicine;Alanine;Amino Acids;Animal Feed;Animal Nutritional Physiological Phenomena;Animals;Cell Line;Diet;Diet, Protein-Restricted;Dietary Proteins;Dietary Supplements;Energy Metabolism;Epithelial Cells;Glutamic Acid;Intestinal Mucosa;Male;Nitrogen;Oxidation-Reduction;Pyruvic Acid;Swine;Urea
期刊:
JOURNAL OF ANIMAL SCIENCE
ISSN:
0021-8812
年:
2018
卷:
96
期:
9
页码:
3804-3814
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31772610]; National "948" Project from the Ministry of Agriculture of China [2015Z74]; National Science and Technology Major Project of China [2017YFD0500504]
机构署名:
本校为其他机构
院系归属:
动物科学与营养工程学院
摘要:
This study was performed to determine if pyruvate, which acts as a critical intermediate in energy metabolism, can substitute the role of glutamate as a metabolic fuel and effectively reduce nitrogen excretion in pigs. First, the experiment in vitro was carried out to investigate the effects of culturing porcine small intestinal epithelial cell line with pyruvate on the oxidation. Then, barrows weighing 40 kg were used in the experiment investigating the changes of nitrogen balance in response to addition of pyruvate to low-protein diets. Last,...

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