期刊论文

Liu, Liangzhong;Zhu, Z

英文

Food Bioscience

2212-4292

2025

64

105828

10.1016/j.fbio.2025.105828

CRediT authorship contribution statement Zhengyu Wang: Writing – original draft, Visualization, Validation, Methodology, Investigation, Formal analysis, Data curation. Quanhong Lv: Validation, Software, Methodology, Investigation. Liangzhong Liu: Writing – review & editing, Supervision, Project administration, Conceptualization. Zhe Zhu: Resources, Project administration, acquisition, Conceptualization.

本校为第一且通讯机构

Constipation is a gastrointestinal disorder related to intestinal flora imbalance and inflammation. Numerous clinical studies have affirmed the efficacy of psyllium husk powder (PHP) in alleviating constipation; however, the efficacy and specific mechanism of PHP in alleviating constipation still lack comprehensive and in-depth discussions. In this study, we comprehensively investigated the mechanism by which round-bracted psyllium husk powder improves loperamide hydrochloride-induced constipation in mice, focusing on gut microbiota and fecal metabolic profiles while comparing the effects of P...