期刊论文

中文

黑龙江畜牧兽医

1004-7034

2020

08

105-109

10.13881/j.cnki.hljxmsy.2019.04.0330

国家自然科学基金项目(31572572)。

本校为第一机构

为了研究黄芩苷对脂多糖（LPS）诱导后仔猪临床症状及血液学指标的影响,试验选取36头健康仔猪,分为空白对照组、LPS模型组、氟尼辛葡甲胺组、黄芩苷低剂量（25 mg/kg）组、黄芩苷中剂量（50 mg/kg）组和黄芩苷高剂量（100 mg/kg）组。各组猪在注射LPS前0.5 h给药,黄芩苷各剂量组及模型组猪按体重0.1 mg/kg腹腔注射LPS,空白对照组猪注射等量生理盐水,LPS诱导6 h后再给药1次。于注射LPS 3 h后测量各组猪的体温,并统计呕吐、颤抖、嗜睡猪的头数;于注射LPS后第3,24小时对各组猪采血,检测血常规指标和血液生化指标。结果表明:LPS诱导后第3小时,LPS模型组猪出现体温升高、颤抖、呕吐和嗜睡等临床症状,...

In order to study the effects of baicalin on the clinical manifestations and hematological parameters induced by lipopolysaccharide(LPS)in piglets,36 healthy piglets were selected,divided into LPS model group,flunixin meglumine group,baicalin low dose(25 mg/kg)group,baicalin midle dose(50 mg/kg)group and baicalin high dose(100 mg/kg)group,respectively.The piglets were administered 0.5 h before the injection of LPS.The baicalin dose group and the model group were intraperitoneally injected with LPS at 0.1 mg/kg bw,and the control group was injected with the same amount of normal saline.The LPS ...