Medium-chain TAG improve intestinal integrity by suppressing toll-like receptor 4, nucleotide-binding oligomerisation domain proteins and necroptosis signalling in weanling piglets challenged with lipopolysaccharide
This study was financially supported by the National Natural Science Foundation of China (31772615, 31422053 and 31372318), State’s Key Project of Research and Development Plan (2016YFD0501210) and the Project of the Hubei Provincial Department of Education (T201508).
机构署名：
本校为第一且通讯机构
院系归属：
动物科学与营养工程学院
摘要：
AbstractThis study was conducted to evaluate whether medium-chain TAG (MCT) could alleviate Escherichia coli lipopolysaccharide (LPS)-induced intestinal injury by regulating intestinal epithelial inflammatory response, as well as necroptosis. A total of twenty-four weanling piglets were randomly allotted to one of four treatments in a 2×2 factorial arrangement including diet type (5 % maize oil v. 4 % MCT+1 % maize oil) and immune stress (saline v. E. coli LPS). The piglets were fed diets containing maize oil or MCT for 21 d. On 21 d, piglets ...
