Main effect and mechanism of NAC on PEDV‐induced intestinal injury in piglets. NAC administration can alleviate intestinal injury while promote viral replication by inhibiting interferon signaling. Scope This study investigates the potential effects of N‐acetylcysteine (NAC) on intestinal injury in a porcine epidemic diarrhea virus (PEDV)‐infected porcine model. Methods and results Thirty‐two piglets are randomly assigned to one of four groups: the control, PEDV, NAC, and NAC+PEDV. Piglets in the NAC+PEDV group are orally administrated with...