Plasma and tissue kinetics of enrofloxacin and its metabolite, ciprofloxacin, in yellow catfish (Pelteobagrus fulvidraco) after a single oral administration at different temperatures

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成果类型：

期刊论文

作者：

Xu, Ning*;Sun, Weiyu;Zhang, Huan;Liu, Yongtao;Dong, Jing;...

通讯作者：

Xu, Ning;Ai, XH

作者机构：

[Liu, Yongtao; Zhang, Huan; Ai, Xiaohui; Yang, Qiuhong; Xu, Ning; Sun, Weiyu; Yang, Yibin; Dong, Jing; Zhou, Shun] Chinese Acad Fishery Sci, Yangtze River Fisheries Res Inst, Wuhan 430223, Peoples R China.

[Liu, Yongtao; Ai, Xiaohui; Yang, Qiuhong; Xu, Ning; Yang, Yibin; Dong, Jing; Zhou, Shun] Hu Bei Prov Engn & Technol Res Ctr Aquat Prod Qual, Wuhan 430223, Peoples R China.

[Zhang, Huan; Sun, Weiyu] Wuhan Polytech Univ, Coll Food Sci & Engn, Wuhan 430023, Peoples R China.

[Xu, Ning; Ai, Xiaohui; Ai, XH] Chinese Acad Fishery Sci, Yangtze River Fisheries Res Inst, 8 Wuda Pk Rd 1, Wuhan 430223, Hubei, Peoples R China.

通讯机构：

[Xu, N; Ai, XH ] C

Chinese Acad Fishery Sci, Yangtze River Fisheries Res Inst, 8 Wuda Pk Rd 1, Wuhan 430223, Hubei, Peoples R China.

语种：

英文

关键词：

Ciprofloxacin;Different temperatures;Enrofloxacin;Pharmacokinetics;Yellow catfish

期刊：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

ISSN：

1532-0456

年：

2023

卷：

266

页码：

109554

DOI：

10.1016/j.cbpc.2023.109554

基金类别：

The authors would like to appreciate the financial support from the National Natural Science Foundation of China ( 32173022 ), the Agriculture Research System of China ( CARS-46 ), the National Key Research and Development Program of China ( 2019YFD0901701 ), and the Major Technological Innovation of Hubei Province of China ( 2019ABA077 ).

机构署名：

本校为其他机构

院系归属：

食品科学与工程学院

摘要：

The objective of this study was to examine the pharmacokinetic (PK) properties of enrofloxacin (EF) and its metabolite, ciprofloxacin (CF), in yellow catfish ( Pelteobagrus fulvidraco ) after a single oral dose of EF at 20 mg/kg at 20, 25, and 30 °C. Samples were collected at pre-designed time points and determined by high-performance liquid chromatography with a fluorescent detector. Results showed that most concentrations of EF and CF in plasma and tissues at the same time point at different temperatures were statistically significant. With ...

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Plasma and tissue kinetics of enrofloxacin and its metabolite, ciprofloxacin, in yellow catfish (Pelteobagrus fulvidraco) after a single oral administration at different temperatures

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