Determination of doxycycline’s plasma protein binding rates in the plasma of grass carp (Ctenopharyngodon idella), yellow catfish (Pelteobagrus fulvidraco) and crayfish (Procambarus clarkii) by an ultrafiltration method at different temperatures with different concentrations

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Sun, Weiyu;Chang, Chao;Xu, Ning*;Wu, Jine;Liu, Yongtao;...

通讯作者：

Chang, C;Xu, Ning;Ai, XH

作者机构：

[Chang, Chao; Sun, Weiyu; Wu, Jine] Wuhan Polytech Univ, Coll Food Sci & Engn, 68 South Xuefu Rd, Wuhan 430023, Hubei, Peoples R China.

[Sun, Weiyu; Ai, Xiaohui; Zhou, Shun; Xu, Ning; Liu, Yongtao; Yang, Qiuhong; Yang, Yibin; Dong, Jing] Chinese Acad Fishery Sci, Yangtze River Fisheries Res Inst, 8 Wuda Pk Rd 1, Wuhan 430223, Hubei, Peoples R China.

[Zhou, Shun; Liu, Yongtao; Ai, Xiaohui; Yang, Qiuhong; Xu, Ning; Yang, Yibin; Dong, Jing] Hu Bei Prov Engn & Technol Res Ctr Aquat Prod Qua, Wuhan, Peoples R China.

通讯机构：

[Xu, N; Ai, XH ] C

[Chang, C ] W

Wuhan Polytech Univ, Coll Food Sci & Engn, 68 South Xuefu Rd, Wuhan 430023, Hubei, Peoples R China.

Chinese Acad Fishery Sci, Yangtze River Fisheries Res Inst, 8 Wuda Pk Rd 1, Wuhan 430223, Hubei, Peoples R China.

语种：

英文

关键词：

doxycycline;plasma protein binding rate;temperature;ultrafiltration

期刊：

Aquaculture Research

ISSN：

1355-557X

年：

2022

卷：

期：

页码：

2865-2873

DOI：

10.1111/are.15801

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [32173022]; Major Technological Innovation of Hubei Province of China [2019ABA077]; Hubei Province Natural Science FoundationNatural Science Foundation of Hubei Province [2019CFB636]

机构署名：

本校为第一且通讯机构

院系归属：

食品科学与工程学院

摘要：

The objective of this study was to compare the plasma protein binding rates (PPBRs) of doxycycline (DC) in the plasma of grass carp (Ctenopharyngodon idella), yellow catfish (Pelteobagrus fulvidraco) and crayfish (Procambarus clarkii) at different temperatures (4, 18 and 25℃) with different concentrations (1, 5, 10 and 20 μg/ml). A rapid and simple method of ultrafiltration (UF) was employed to determine the PPBR of DC in the plasma. The results showed that PPBRs were increased with the rise of the concentration of DC at the same temperature....

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Determination of doxycycline’s plasma protein binding rates in the plasma of grass carp (Ctenopharyngodon idella), yellow catfish (Pelteobagrus fulvidraco) and crayfish (Procambarus clarkii) by an ultrafiltration method at different temperatures with different concentrations

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