Molecular cloning, distribution and ontogenetic expression of the oligopeptide transporter PepT1 mRNA in Tibetan suckling piglets

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成果类型：

期刊论文

作者：

Wang, Wence;Shi, Changyou;Zhang, Jianshe;Gu, Wanting;Li, Tiejun;...

通讯作者：

Chu, Wuying

作者机构：

[Huang, Ruilin; Chu, Wuying; Li, Peng; Gen, Meimei; Li, Tiejun; Yin, Yulong; Shi, Changyou; Wang, Wence; Gu, Wanting] Chinese Acad Sci, Inst Subtrop Agr, Lab Anim Nutr Physiol & Metab Proc, Changsha 410125, Hunan, Peoples R China.

[Zhang, Jianshe; Chu, Wuying] Changsha Univ, Dept Bioengn & Environm Sci, Changsha 410003, Hunan, Peoples R China.

[Liu, Yulan; Hou, Yongqing; Yin, Yulong] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Peoples R China.

[Chu, Wuying] Chinese Acad Sci, Inst Subtrop Agr, Lab Anim Nutr Physiol & Metab Proc, POB 10, Changsha 410125, Hunan, Peoples R China.

通讯机构：

[Chu, Wuying] C

Chinese Acad Sci, Inst Subtrop Agr, Lab Anim Nutr Physiol & Metab Proc, POB 10, Changsha 410125, Hunan, Peoples R China.

语种：

英文

关键词：

Amino acid transporter;PepT1;Tibetan pig;Expression

期刊：

Amino Acids

ISSN：

0939-4451

年：

2009

卷：

期：

页码：

593-601

DOI：

10.1007/s00726-008-0178-7

基金类别：

Dr. Peng Li thanks K. C.Wong Education Foundation, Hong Kong for financial supporting. This research was jointly supported by grants from the Chinese Academy of Sciences and Knowledge Innovation Projects (Kscx2-Yw-N-051, KSCX2-SW-323 and YW-N-022), the National Basic Research Program of China (2004CB117502), the National Natural Science Foundation of China (30528006, 30671517,30771558,30700581 and 30371038), Hunan Key Project (2007FJ1003) and National Scientific and Technological Supporting Projects (2006BAD12B07 and 2006BAD12B02-5).

机构署名：

本校为其他机构

院系归属：

动物科学与营养工程学院

摘要：

The gene encoding the oligopeptide transporter PepT1 (HGMW-approved gene symbol SLC15A1) from Tibetan porcine intestine was cloned. The open reading frame of this cDNA encodes 708 deduced amino acid residues that show high sequence similarity with its ovine and bovine counterparts. The putative protein has 12 putative transmembrane domains, including many structural features that are highly conserved among the vertebrate orthologs. PepT1 mRNA expression can be detected in duodenum, jejunum and ileum from Tibetan pigs at 28 days by RT-PCR. Real-...

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Molecular cloning, distribution and ontogenetic expression of the oligopeptide transporter PepT1 mRNA in Tibetan suckling piglets

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