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Fucoidan Alleviates Porcine Epidemic Diarrhea Virus-Induced Intestinal Damage in Piglets by Enhancing Antioxidant Capacity and Modulating Arginine Metabolism

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成果类型:
期刊论文
作者:
Zhang, Qian;Wang, Maojing;Li, Zhonghua;Zhao, Di;Hou, Yongqing;...
通讯作者:
Wu, T
作者机构:
[Wu, Tao; Wu, T; Hou, Yongqing; Wang, Maojing; Zhang, Qian; Li, Zhonghua; Zhao, Di] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Peoples R China.
通讯机构:
[Wu, T ] W
Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Peoples R China.
语种:
英文
关键词:
antioxidant;arginine metabolism;fucoidan;intestinal damage;piglets;porcine epidemic diarrhea virus
期刊:
ANIMALS
ISSN:
2076-2615
年:
2025
卷:
15
期:
7
基金类别:
Hubei Provincial Department of Education Innovative Team Project; National Natural Science Foundation of China [32302781]; Natural Science Foundation of Hubei Province [2024AFB942]; [T2023010]
机构署名:
本校为第一且通讯机构
院系归属:
动物科学与营养工程学院
摘要:
Porcine epidemic diarrhea virus (PEDV) causes severe intestinal damage, posing significant threats to the swine industry. Fucoidan (FUC), a biologically active compound, exhibits antiviral activity against multiple viruses. This study aimed to investigate the protective effects of FUC on PEDV-induced intestinal injury in piglets and explore its underlying mechanisms. A total of 28 healthy crossbred piglets were randomly allocated into four experimental groups using a 2 × 2 factorial design: (1) a control group, (2) an FUC group, (3) a PEDV gro...

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