Objective To explore the dymamic variation in brain edema after the focal cerebral ischemia. Methods We determined changes of brain water content after middle cerebral artery occlusion (MCAO) .Twenty-eight normal SD rats(200~300g,female or male) were randomly divided into three groups:the normal group(n=4),the false operation group(n=4) and the ischemical injury group(n=20,each 4 of them were respctively observed at 2h,4h,8h,15h and 30h after MCAO). Results It was found that the water contents of brain tissues in normal group were similar to t...