期刊论文

The Effect of Intrathecal Injection of Emodin Nanoemulsion on Bone Cancer Pain in Rats

中文

湖北科技学院学报(医学版)

2095-4646

2023

37

02

99-103

10.16751/j.cnki.2095-4646.2023.02.099

武汉市中医药科研项目(WZ22C10)。

本校为其他机构

目的探讨大黄素纳米乳在大鼠骨癌痛模型中的镇痛效应。方法18只SD大鼠随机分为假手术组、模型组和大黄素组,每组6只。模型组和大黄素组均采用胫骨髓腔注射大鼠乳腺癌MRMT-1细胞建立骨癌痛模型,假手术组仅在胫骨髓腔内注射相同...展开更多 目的探讨大黄素纳米乳在大鼠骨癌痛模型中的镇痛效应。方法18只SD大鼠随机分为假手术组、模型组和大黄素组,每组6只。模型组和大黄素组均采用胫骨髓腔注射大鼠乳腺癌MRMT-1细胞建立骨癌痛模型,假手术组仅在胫骨髓腔内注射相同体积的Hank’s液。造模15d后,大黄素组单次鞘内注射5mg/mL大黄素纳米乳10μL,而模型组与假手术组注射相同体积生理盐水。采用X线、HE染...

Objective To investigate the analgesic effect of emodin nanoemulsion in rats with bone cancer pain model.Methods Eighteen SD rats were randomly divided into sham operation group,model group and emodin group,with 6 rats in each group.The model group and emodin group were...MORE Objective To investigate the analgesic effect of emodin nanoemulsion in rats with bone cancer pain model.Methods Eighteen SD rats were randomly divided into sham operation group,model group and emodin group,with 6 rats in each group.The model group and emodin group were i...