Schizopygopsis pylzovi Kessler (Cypriniformes: Cyprinidae), an endemic species to China, is a major commercial fish in the upper reaches of the Yellow River. The complete mitochondrial DNA genome of S. pylzovi was sequenced. The mitogenome is 16,704 bp in length and includes 13 protein-coding genes, 22 transfer RNA genes, two ribosomal RNA genes and two non-coding regions. The basic composition of S. pylzov is 28.5% for A, 27.0% for T, 26.1% for C, and 18.4% for G, with a slight AT bias of 55.5%. Gene order is similar to that of the typical ver...