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Sesame cake hydrolysates improved spatial learning and memory of mice

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成果类型:
期刊论文
作者:
Shu, Zaixi;Liu, Lingyi*;Geng, Pengfei;Liu, Jiawei;Shen, Wangyang;...
通讯作者:
Liu, Lingyi
作者机构:
[Geng, Pengfei; Shen, Wangyang; Liu, Lingyi; Shu, Zaixi; Tu, Mengjie] Wuhan Polytech Univ, Coll Food Sci & Engn, Wuhan 430023, Hubei, Peoples R China.
[Liu, Jiawei] Shandong Acad Agr Machinery Sci, Jinan 250100, Shandong, Peoples R China.
通讯机构:
[Liu, Lingyi] W
Wuhan Polytech Univ, Coll Food Sci & Engn, Wuhan 430023, Hubei, Peoples R China.
语种:
英文
关键词:
Memory;mRNA;Sesame cake hydrolysates;Sesamum indicum L
期刊:
Food Bioscience
ISSN:
2212-4292
年:
2019
卷:
31
页码:
100440
基金类别:
Natural Science Foundation of Hubei ProvinceNatural Science Foundation of Hubei Province [2017CFB308]; Natural Science of Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31601476]; Foundation of Wuhan Polytechnic University [2016RZ21]
机构署名:
本校为第一且通讯机构
院系归属:
食品科学与工程学院
摘要:
Age-related decrease in cognition function was shown to be related to oxidative stress, and the study investigated the effect of sesame cake hydrolysates (SCH) on the improvement of learning and memory in mice using the Morris water maze (MWM) test. The mice administered a medium dose (20 mg/kg/d) of SCH did better in learning and memory function compared with the low-dose (10 mg/kg/d), and high-dose (30 mg/kg/d) treated animals with no significant differences in body weight. Biochemical analysis (SOD, GSH-Px, MDA, NO, and AChE) showed SCH impr...

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