期刊论文

Jin-Long Li

英文

Food and Chemical Toxicology

0278-6915

2023

174

113655

10.1016/j.fct.2023.113655

This study has received assistance from National Natural Science Foundation of China (No. 32172932 , 32002346 ), Key Program of Natural Science Foundation of Heilongjiang Province of China (No. ZD2021C003 ), China Agriculture Research System of MOF and MARA (No. CARS-35 ), Distinguished Professor of Longjiang Scholars Support Project (No. T201908 ) and Heilongjiang Touyan Innovation Team Program . The funder of the study had no role in study design, data collection, data analysis, data interpretation, or writing of the report.

本校为其他机构

Atrazine (ATR) is a commercially available herbicide that is used worldwide. The intensive use of ATR poses potential risks to animals' and humans’ health. Lycopene (LYC) is an anti-oxidative phytochemical that normalizes health hazards triggered by environmental factors. In this study, we aimed to investigate the toxic effects of ATR on the hippocampus and its amelioration by LYC. Male mice were exposed to ATR (50 mg/kg/day or 200 mg/kg/d) and/or LYC (5 mg/kg/d) for 21 days. The results showed that ATR exposure induced hippocampus-dependent l...