Real role of growth factor receptor-binding protein 10: Linking lipid metabolism to diabetes cardiovascular complications

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成果类型：

期刊论文

作者：

Yang, Yang;Yao, Hua-Jie;Lin, Wei-Jie;Huang, Si-Chao;Li, Xiao-Dong;...

通讯作者：

He, Fa-Zhong

作者机构：

[Huang, Si-Chao; Lin, Wei-Jie; Yang, Yang] Jinan Univ, Zhuhai Peoples Hosp, Dept Pharm, Zhuhai 519000, Guangdong, Peoples R China.

[Yao, Hua-Jie] Wuhan Polytech Univ, Coll Life Sci & Technol, Wuhan 430000, Hubei, Peoples R China.

[Li, Xiao-Dong; He, Fa-Zhong] Jinan Univ, Zhuhai Peoples Hosp, Dept Qual Control, Zhuhai 519000, Guangdong, Peoples R China.

[He, Fa-Zhong] Jinan Univ, Zhuhai Peoples Hosp, Dept Qual Control, 79 Kangning Rd, Zhuhai 519000, Guangdong, Peoples R China.

通讯机构：

[He, Fa-Zhong] D

Department of Quality Control, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Zhuhai 519000, Guangdong Province, China.

语种：

英文

关键词：

Growth factor receptor-binding protein 10;Lipid metabolism;Type 2 diabetes mellitus;Vascular complications

期刊：

世界临床病例杂志

ISSN：

2307-8960

年：

2022

卷：

期：

页码：

12875-12879

DOI：

10.12998/wjcc.v10.i35.12875

基金类别：

Zhuhai People's Hospital [2009PY-09]; National Scientific Foundation of China [81903715]

机构署名：

本校为其他机构

院系归属：

生命科学与技术学院

摘要：

Cardiovascular complications of patients with type 2 diabetes mellitus (T2DM) threaten the health and life of numerous individuals. Recently, growth factor receptor-binding protein 10 (GRB10) was found to play a pivotal role in vascular complications of T2DM, which participates in the regulation of lipid metabolism of T2DM patients. The genetic variation of GRB10 rs1800504 is closely related to the risk of coronary heart disease in patients with T2DM. The development of GRB10 as a key mediator in the association of lipid metabolism with cardiovascular complications in T2DM is detailed in and m...

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Real role of growth factor receptor-binding protein 10: Linking lipid metabolism to diabetes cardiovascular complications

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