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Identification of the potential novel biomarkers as susceptibility gene for Wilms tumor

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成果类型:
期刊论文
作者:
Liu, Li;Song, Zhe;Gao, Xu-Dong;Chen, Xian;Wu, Xiao-Bin;...
通讯作者:
Zhe Song
作者机构:
[Song, Zhe; Liu, Li; Wu, Xiao-Bin; Wang, Mi; Hong, Yu-De; Chen, Xian] Univ South China, Hosp 2, Dept Urol, Hengyang 421001, Hunan, Peoples R China.
[Gao, Xu-Dong] Wuhan Polytech Univ, Coll Hlth Sci & Nursing, Wuhan 420000, Peoples R China.
通讯机构:
[Zhe Song] D
Department of Urology, The Second Hospital, University of South China, Hengyang, China
语种:
英文
关键词:
Wilms tumor;Biomarkers;Recurrence;Overall survival
期刊:
BMC Cancer
ISSN:
1471-2407
年:
2021
卷:
21
期:
1
页码:
1-15
基金类别:
None.
机构署名:
本校为其他机构
院系归属:
医学与健康学院
摘要:
Wilms tumor (WT) is the most common malignant renal tumor in children. The aim of this study was to identify potential susceptibility gene of WT for better prognosis. Weighted gene coexpression network analysis is used for the detection of clinically important biomarkers associated with WT. In the study, 59 tissue samples from National Cancer Institute were pretreated for constructing gene co-expression network, while 224 samples also downloaded from National Cancer Institute were used for hub gene validation and module preservation analysis. Three modules were found to be highly correlated wi...

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