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Robust and facile label-free colorimetric aptasensor for ochratoxin A detection using aptamer-enhanced oxidase-like activity of MnO2 nanoflowers

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成果类型:
期刊论文
作者:
Lv, Xuqin;Foda, Mohamed Frahat;He, Jiangling;Zhou, Jiaojiao;Cai, Jie
通讯作者:
Zhou, Jiaojiao(jiaojiaozhou@whpu.edu.cn)
作者机构:
[He, Jiangling; Zhou, Jiaojiao; Cai, Jie; Lv, Xuqin] Wuhan Polytech Univ, Natl R&D Ctr Serich Agr Prod Proc, Hubei Engn Res Ctr Deep Proc Green Se rich Agr Pro, Sch Modern Ind Selenium Sci & Engn, Wuhan 430023, Peoples R China.
[He, Jiangling; Zhou, Jiaojiao; Cai, Jie; Lv, Xuqin] Wuhan Polytech Univ, Key Lab Deep Proc Major Grain & Oil, Hubei Key Lab Proc & Transformat Agr Prod, Minist Educ, Wuhan 430023, Peoples R China.
[Foda, Mohamed Frahat] Huazhong Agr Univ, Coll Sci, Coll Vet Med, State Key Lab Agr Microbiol, Wuhan 430070, Peoples R China.
[Foda, Mohamed Frahat] Benha Univ, Fac Agr, Dept Biochem, Moshtohor 13736, Egypt.
通讯机构:
[Jiaojiao Zhou; Jie Cai] N
National R&D Center for Se-rich Agricultural Products Processing, Hubei Engineering Research Center for Deep Processing of Green Se-rich Agricultural Products, School of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, China<&wdkj&>Key Laboratory for Deep Processing of Major Grain and Oil, Ministry of Education, Hubei Key Laboratory for Processing and Transformation of Agricultural Products, Wuhan Polytechnic University, Wuhan 430023, China
语种:
英文
关键词:
Aptamer;Colorimetric detection;Food samples;MnO(2) nanoflowers;Ochratoxin A
期刊:
Food Chemistry
ISSN:
0308-8146
年:
2023
卷:
401
页码:
134144
基金类别:
CRediT authorship contribution statement Xuqin Lv: Conceptualization, Methodology, Data curation, Formal analysis, Writing – original draft. Mohamed Frahat Foda: Investigation. Jiangling He: Software, Formal analysis, Data curation. Jiaojiao Zhou: Conceptualization, Formal analysis, Supervision, Project administration, acquisition, Writing – review & editing. Jie Cai: Formal analysis, Supervision, Project administration, acquisition, Writing – review & editing.
机构署名:
本校为第一机构
院系归属:
食品科学与工程学院
硒科学与工程现代产业学院
摘要:
Ochratoxin A (OTA) is a powerful mycotoxin that can cause severe damage to human health, and its detection has attracted considerable attention in the field of food science. We present a robust and facile label-free colorimetric aptasensor for OTA detection using the aptamer-enhanced oxidase-like activity of MnO2 nanoflowers. The catalytic activities of the nanozymes could be improved by adsorption of the aptamers onto the MnO2 nanoflowers due to the increased affinity of the nanoflowers for the chromogenic substrate. The linear range for OTA d...

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