版权说明 操作指南
首页 > 成果 > 详情

A data-driven integrative platform for computational prediction of toxin biotransformation with a case study

认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Zhang, Dachuan;Tian, Ye;Tian, Yu;Xing, Huadong;Liu, Sheng;...
通讯作者:
Wu, Aibo;Hu, Qian-Nan
作者机构:
[Liu, Sheng; Cai, Pengli; Sun, Dandan; Zhang, Dachuan; Wu, Aibo; Hu, QN; Xing, Huadong; Hu, Qian-Nan; Hong, Yanhong; Zhang, Tong; Tian, Ye; Ding, Shaozhen] Univ Chinese Acad Sci, Chinese Acad Sci, CAS MPG Partner Inst Computat Biol,CAS Key Lab Nu, Shanghai Inst Nutr & Hlth,CAS Key Lab Computat Bi, Shanghai 200031, Peoples R China.
[Tian, Yu] Wuhan Polytech Univ, Sch Biol & Pharmaceut Engn, Wuhan 430023, Peoples R China.
[Zhang, Haoyang] Shaanxi Normal Univ, Coll Food Engn & Nutr Sci, Xian 710119, Peoples R China.
[Cai, Pengli] Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Tianjin 300308, Peoples R China.
[Dai, Hongkun] Shandong Runda Testing Technol Co Ltd, Weifang 261000, Peoples R China.
通讯机构:
[Wu, AB; Hu, QN] U
Univ Chinese Acad Sci, Chinese Acad Sci, CAS MPG Partner Inst Computat Biol,CAS Key Lab Nu, Shanghai Inst Nutr & Hlth,CAS Key Lab Computat Bi, Shanghai 200031, Peoples R China.
语种:
英文
关键词:
Bioinformatics;Cheminformatics;Metabolites;Synthesis biology;Systems biology
期刊:
Journal of Hazardous Materials
ISSN:
0304-3894
年:
2021
卷:
408
页码:
124810
基金类别:
and acknowledgements This work was supported by the National Key Research and Development Program of China [grant numbers 2019YFA0904300, 2018YFA0900700, and 2017YFC1601702], Science and Technology Service Network Initiative of Chinese Academy of Sciences [KFJ-STS-ZDTP-084, QYZDB-SSW-SMC012], Shanghai Agriculture Applied Technology Development Program, China [2019-02-08-00-02-F01145], National Natural Science Foundation of China [grant numbers 31700081, 31772087, and 31570092], China Postdoctoral Science Foundation CRediT authorship contribution statement Dachuan Zhang: Conceptualization, Methodology, Writing - original draft, Writing - review & editing. Ye Tian: Conceptualization, Methodology, Writing - original draft, Writing - review & editing. Yu Tian: Conceptualization, Methodology, Writing - original draft, Writing - review & editing. Huadong Xing: Investigation, Software, Data curation. Sheng Liu: Investigation, Data curation. Haoyang Zhang: Investigation, Data curation. Shaozhen Ding: acquisition. Pengli Cai: Data curation.
机构署名:
本校为其他机构
院系归属:
生命科学与技术学院
摘要:
Recently, biogenic toxins have received increasing attention owing to their high contamination levels in feed and food as well as in the environment. However, there is a lack of an integrative platform for seamless linking of data-driven computational methods with 'wet' experimental validations. To this end, we constructed a novel platform that integrates the technical aspects of toxin biotransformation methods. First, a biogenic toxin database termed ToxinDB (http://www.rxnfinder.org/toxindb/), containing multifaceted data on more than 4836 toxins, was built. Next, more than 8000 biotransform...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com