Chitosan-coated soybean protein isolate/lecithin nanoparticles for enhancing the stability and bioaccessibility of phytosterol

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成果类型：

期刊论文

作者：

Ming Cheng;Ye Tao;Chunwei Wang;Ao Li;Ming Cheng Ming Cheng Ming Cheng;...

通讯作者：

Ao Li<&wdkj&>Ao Li Ao Li Ao Li

作者机构：

Department of Food Science and Pharmaceutics, Zhejiang Ocean University, Zhoushan, China

Department of Food Science and Technology, Wuhan Polytechnic University, Wuhan, China

Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, China

Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang, China

[Ming Cheng; Ye Tao; Ming Cheng Ming Cheng Ming Cheng; Ye Tao Ye Tao Ye Tao] Department of Food Science and Pharmaceutics, Zhejiang Ocean University, Zhoushan, China<&wdkj&>Department of Food Science and Technology, Wuhan Polytechnic University, Wuhan, China

通讯机构：

[Ao Li; Ao Li Ao Li Ao Li] D

Department of Food Science and Technology, Wuhan Polytechnic University, Wuhan, China<&wdkj&>Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang, China

语种：

英文

关键词：

chitosan;drug carrier;nanoparticle;phosphatidylcholine;phytosterol;soybean protein;chemistry;human;particle size;Chitosan;Drug Carriers;Humans;Lecithins;Nanoparticles;Particle Size;Phytosterols;Soybean Proteins

期刊：

Journal of the Science of Food and Agriculture

ISSN：

0022-5142

年：

2024

卷：

104

期：

页码：

4242-4250

DOI：

10.1002/jsfa.13307

基金类别：

The authors are grateful for the financial support of the Special Fund for Introduced Talent to Initiate Scientific Research of Zhejiang Ocean University (JX6311131623) and the Open Project of Hubei Key Laboratory of Animal Nutrition and Feed Science (DKXY2020012).

机构署名：

本校为通讯机构

院系归属：

动物科学与营养工程学院

摘要：

BACKGROUND: Phytosterols (PS) have various beneficial effects on human health, especially the property of reducing blood cholesterol. However, the low solubility and bioaccessibility of PS have greatly limited their application in functional food ingredients. RESULTS: To improve the bioaccessibility and stability of PS, chitosan-coated PS nanoparticles (CS-PNP) were successfully prepared by self-assembly. The properties of CS-PNP, including size, zeta potential, encapsulation efficiency (EE) and loading amount (LA) were characterised. The optim...

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Chitosan-coated soybean protein isolate/lecithin nanoparticles for enhancing the stability and bioaccessibility of phytosterol

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