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Study on the Effects and Mechanism of Corilagin on A2780 Cell Apoptosis

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成果类型:
期刊论文
作者:
Xu, Ziyang;Jiang, Yuhan;Shan, Tiantian;Hu, Lei;Wu, Minrui;...
通讯作者:
Wang, LM
作者机构:
[Wang, Hongxun; Wu, Minrui; Xu, Ziyang; Li, Longjie; Wang, Limei; Wang, LM; Shan, Tiantian; Ji, Hanxu; Hu, Lei] Wuhan Polytech Univ, Coll Life Sci & Technol, Wuhan 430023, Peoples R China.
[Jiang, Yuhan] Huazhong Univ Sci & Technol, Coll Life & Sci, Wuhan 430023, Peoples R China.
[Yi, Yang] Wuhan Polytech Univ, Coll Food Sci & Engn, Wuhan 430023, Peoples R China.
通讯机构:
[Wang, LM ] W
Wuhan Polytech Univ, Coll Life Sci & Technol, Wuhan 430023, Peoples R China.
语种:
英文
关键词:
corilagin;ovarian cancer;apoptosis;mechanism;p53 signaling pathway
期刊:
CURRENT ISSUES IN MOLECULAR BIOLOGY
ISSN:
1467-3037
年:
2025
卷:
47
期:
2
页码:
105-
基金类别:
Writing—original draft, Z.X.; writing—review and editing—Y.J.; data curation—T.S.; visualization—L.H.; investigation—M.W.; formal analysis—H.J.; supervision—L.L.; methodology—Y.Y.; project administration—H.W.; funding acquisition—L.W. All authors have read and agreed to the published version of the manuscript. This work was supported by the Hubei Province Natural Science Foundation of China (2022CFB429) and the Primary Research and Development Plan of Hubei Province (2022BBA0023).
机构署名:
本校为第一且通讯机构
院系归属:
食品科学与工程学院
生命科学与技术学院
摘要:
Previous studies have demonstrated corilagin’s inhibitory effects on the growth of various cancer cells. Given the limited research on corilagin’s impact on ovarian cancer, a particularly deadly gynecological malignancy, this study aimed to investigate corilagin’s influence on A2780 ovarian cancer cell apoptosis and its underlying mechanisms. The goal was to evaluate corilagin’s potential as a therapeutic agent for ovarian cancer. The results of the CCK-8 assay showed that corilagin inhibited the proliferation of A2780 ovarian cancer cells ...

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