prfA-Like Transcription Factor Gene lmo0753 Contributes to L-Rhamnose Utilization in Listeria monocytogenes Strains Associated with Human Food-Borne Infections

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成果类型：

期刊论文

作者：

Salazar, Joelle K.;Wu, Zhuchun;McMullen, P. David;Luo, Qin;Freitag, Nancy E.;...

通讯作者：

Zhang, Wei

作者机构：

[Salazar, Joelle K.; Zhang, Wei; Wu, Zhuchun] IIT, Inst Food Safety & Hlth, Bedford Pk, IL USA.

[McMullen, P. David; Freitag, Nancy E.] Univ Illinois, Coll Med, Dept Microbiol & Immunol, Chicago, IL 60612 USA.

[Luo, Qin] Huazhong Normal Univ, Coll Life Sci, Wuhan, Peoples R China.

[Tortorello, Mary Lou] US FDA, Bedford Pk, IL USA.

[Zhang, Wei; Hu, Shencai] Wuhan Polytech Univ, Sch Biol & Pharmaceut Engn, Wuhan, Peoples R China.

通讯机构：

[Zhang, Wei] I

IIT, Inst Food Safety & Hlth, Bedford Pk, IL USA.

语种：

英文

期刊：

Applied and Environmental Microbiology

ISSN：

0099-2240

年：

2013

卷：

期：

页码：

5584-5592

DOI：

10.1128/AEM.01812-13

基金类别：

U.S. Food and Drug Administration research funds; Chu Tian Lecturing Professorship from the Department of Education of Hubei Province

机构署名：

本校为其他机构

院系归属：

生命科学与技术学院

摘要：

Listeria monocytogenes is a food-borne bacterial pathogen and the causative agent of human and animal listeriosis. Among the three major genetic lineages of L. monocytogenes (i.e., LI, LII, and LIII), LI and LII are predominantly associated with food-borne listeriosis outbreaks, whereas LIII is rarely implicated in human infections. In a previous study, we identified a Crp/Fnr family transcription factor gene, lmo0753, that was highly specific to outbreak-associated LI and LII but absent from LIII. Lmo0753 shares two conserved functional domain...

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prfA-Like Transcription Factor Gene lmo0753 Contributes to L-Rhamnose Utilization in Listeria monocytogenes Strains Associated with Human Food-Borne Infections

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